Activon Medical Grade Manuka Honey 25g (Pack of 3)

Product Information

All honeys are good for healing skin conditions. They work through the 4 factors from the list above. Here are other details on Activon Manuka Honey from its producer Advances Medical. What is Eclypse? If you need recurring bulk supply for a business, restaurant, or retail store, we can set you up with a business account. This provides benefits like discounted pricing, dedicated account management, and tailored delivery options. Discomfort can be experienced when honey is applied, depending on sensitivity of the wound it may be necessary to consider an appropriate level of analgesia. The initial discomfort usually subsides, however if it does continue, discontinue use and irrigate the wound with saline solution. How to Use

Other floral factors. If honey is made of thyme, it will include the essence of all thyme therapeutic properties. Here we can also add: antioxidants, polyphenols, flavonoids, enzymes and peptides. Safety First: Please note that Activon Tube is not suitable for individuals allergic to bee venom. Some initial discomfort might occur but usually subsides. If persistent, cease use and consult a medical professional. Comvita ®Medihoney ® Antibacterial Wound Gel™, Comvita ® Manuka Medihoney ® and Surgihoney™RO ® enhanced the sensitivity of P. aeruginosa to tetracycline.

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Most effective combination against established S. aureus biofilms was rifampicin and Medihoney. Fusidic acid and Medihoney combination induced some synergistic antimicrobial effects. Kwakman et al (2011) 52 investigated the antimicrobial effects of supplementing Revamil honey with the antimicrobial peptides LL-37 and the synthetic peptide bacterial peptide 2 (BP2). They reported that the antimicrobial activity of LL-37 was inhibited in the presence of honey, but this was not the case for BP2. Using a liquid bactericidal assay, it was shown that Revamil honey supplemented with 75µM BP2 had more rapid antibacterial activity against MRSA and extended spectrum β lactamase (ESBL) E. coli and had a broader spectrum of antibacterial activity than Revamil alone. The authors considered supplementing the honey with hydrogen peroxide or MGO but were concerned that high levels of these components may not be biocompatible. The MIC of the combination of honey, cinnamaldehyde and carvacrol was lower than honey alone (0.49µg/mL vs 114.2 μg/mL respectively). The antibacterial activity of the triple combination was reportedly greater than imipenem. Clindamycin or oxacillin manuka honey combinations demonstrated synergistic antimicrobial activity against most strains (planktonic and biofilm formation) but not all. Whether the enhanced antimicrobial effects were synergistic, or additive was not determined in this study.

The manuka honey comes from New Zealand and is produced following strict quality management and control procedures that ensure the honey remains free from any contaminants. It is also tested to establish the antibacterial level of the manuka honey as a high level is required for medical grade manuka honey.If the area of the wound is showing the classical signs of inflammation: redness, pus, swelling and pain. Surgihoney™RO ® and Comvita ®Medihoney ® Antibacterial Wound Gel™ increased the sensitivity of S. aureus to tetracycline and ampicillin.

Twist off the cap, generously apply to the wound surface or cavity, and cover with a suitable secondary dressing. Shelf LifeHoney and ginger combination induced higher mean zones of inhibition than honey or ginger alone or standard antibiotic discs (methicillin, penicillin, amoxicillin). The first thing that should be done is to remove the cause of the inflammation, which is to kill the infecting bacteria and remove any pus or dead tissue, that provide a medium for their growth. How does honey heal? Hydrogel is commonly used as a wound dressing. It is composed of polymers suspended in water and is thought to provide hydration to a wound and promote healing. El-Kased et al (2017) 53 reported that an Egyptian honey (75%) chitosan hydrogel formula had superior antimicrobial activity against P. aeruginosa, S. aureus, K. pneumonia and Streptococcus pyogenes in a disc diffusion assay in comparison to pure honey. For example, the mean zone of inhibition for the honey 75% chitosan hydrogel formula against S. aureus was 20.2 ± 0.4 vs 15.1 ± 0.9 for honey. This formula was also superior to pure honey in the healing of 10 mm burn wounds induced in mice using a heated metallic rod. The wounds were treated with either the honey 75% chitosan hydrogel formula or honey for 9 days. By day 9, the honey chitosan treated wounds had a mean diameter of 3.8 ± 0.2 mm versus 5.3 ± 0.8 mm in the honey only treated group. Furthermore, an alginate-based honey hydrogel containing thymol-based honey from Damavand, Iran was reported to have superior wound healing ability in rats with infected burn wounds than honey alone. 54 Wound healing was faster in the alginate-based honey hydrogel treated group in comparison to the honey only group. In another study, a paste composed of carboxymethyl cellulose hydrogel (50%), water (30%) and chestnut honey (20%) had superior antimicrobial activity against S. aureus and E.coli in a disc diffusion assay than a paste composed of carboxymethyl cellulose hydrogel (50%) and water only. 55 Furthermore, the paste containing 20% chestnut honey had superior wound healing ability in comparison to the paste without honey in the treatment of wounds inflicted in the dorsal skin of mice. Tavaloki and Tang (2017) 56 designed a wound dressing consisting of a high concentration of honey, polyvinyl alcohol hybrid hydrogel and borax as a crosslinking agent. High concentrations of honey are important for wound healing but can negatively affect the physicochemical properties of hybrid hydrogels. The use of borax apparently overcomes this problem and permits the incorporation of high concentrations of honey without negative effects.